Environmental risk and influence of chemicals from plastic materials on children’s health – the challenge also for paediatricians
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Instytut Medycyny Pracy i Zdrowia Środowiskowego w Sosnowcu Dyrektor: dr n. med. Piotr Z. Brewczyński
Zbigniew Rudkowski   

53-209 Wrocław ul. Wojciecha Męcińskiego 20
Med Srod. 2013;16(1):7–15
Chemicals artificially synthesized and leaching into a common environment are a toxicological risk particularly in prenatal period and in early childhood. The risk exists due to the contact with xenogenic substances from maternal breast milk and other food, polluted air and water, plastic materials, cosmetics. All endocrine and neurological disruptors (EDC) pass across placenta, then can cause hormonal, neurological or metabolic disorders mainly due to estrogenic action. Bisphenol A is one of endocrine disruptors leaching from polychlorobiphenyl plastic (PCB), present commonly in baby polycarbonate bottles. Phtalates like DEHP, DOP, DINP, DIDP, DIPB, DBP or BBP are used as plasticizers making plastics softer and more flexible. Flame retardants f, ex, PBDE (polybrominated diphenyleter) are added to polyurethane foams, and HBCD (hexabromocyclododecane) is a compound of polystyrene electric insulation. Perfluorinated compounds (PFC) are some hundreds substancies and mostly used is PFOS (Perfluoroacetate sulphonate) and PFOA (perfluoroacetic acid) repelling water, grease and dirt; they are used as impregnating and cleaning agents, and PTFE (polytetrafluoroethylen) known as Teflon or Goretex. The toxicity of xenogens for experimental animals is confirmed., but a harmful effect on humans is still discussed what is based only on epidemiological but not experimental studies. Epidemiological studies link human EDC exposure with hormonal, neurological and behavioural distorders f.ex. early maturation of girls, obesity, metabolic syndrome, and type 2 diabetes, and likely weakening of postvaccinal immunity. The awareness on environmental risks is essential for rationale behaviour diminishing the exposition and also being an important element of contemporary health promotion
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