Mechanisms of infection by pathogens transmitted by ticks on the example of bacteria: Anaplasma phagocytophilum and Borrelia burgdorferi
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Zakład Fizyko-Chemicznych Zagrożeń Zdrowotnych i Ekologii, Instytut Medycyny Wsi im. Witolda Chodźki w Lublinie Kierownik Zakładu: dr hab. M. Mojzych, Dyrektor: prof. nadzw. dr hab. I. Bojar
Instytut Ochrony Środowiska – Państwowy Instytut Badawczy w Warszawie Dyrektor: prof. dr hab. B. Gworek
Paula Wróblewska   

Zakład Fizyko-Chemicznych Zagrożeń Zdrowotnych i Ekologii Instytut Medycyny Wsi im. Witolda Chodźki w Lublinie, ul. Jaczewskiego 2, 20-090 Lublin tel. 81 71 84 548
Med Srod. 2016;19(2):63–68
Tick-borne diseases are transmission diseases belonging to the group of zoonoses but carried by ticks. These diseases are a major public health problem but also a problem for groups occupationally exposed to tick bites. Ixodes ricinus is a species of ticks which is the most common reservoir and the vector of a large number of microorganisms pathogenic to humans. It transfers, among others, bacteria of the species: Anaplasma phagocytophilum and Borrelia burgdorferi. The article discusses the mechanisms of infection with Borrelia burgdorferi and Anaplasma phagocytophilum for both ticks as well as for animals and humans. The two microorganisms discussed have developed many characteristics and mechanisms of adaptation to the environment, as well as defense mechanisms against the body's immune response. Understanding the biology of ticks and the function of proteins produced by ticks and pathogenic microorganisms is the key in the development of effective treatments and prevention of Lyme disease and anaplasmosis
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