PRACA POGLĄDOWA
Stężenie selenu we krwi w różnych populacjach osób zdrowych i chorych – przegląd piśmiennictwa z lat 2005–2010
Paweł Gać 1  
,   Krystyna Pawlas 2, 3
 
Więcej
Ukryj
1
Koło Naukowe Zdrowia Środowiskowego i Epidemiologii przy Katedrze i Zakładzie Higieny Akademii Medycznej im. Piastów Śląskich we Wrocławiu. Kierownik: dr hab. n. med. K. Pawlas, prof. nadzw.
2
Katedra i Zakład Higieny Akademii Medycznej im. Piastów Śląskich we Wrocławiu. Kierownik: dr hab. n. med. K. Pawlas, prof. nadzw.
3
Instytut Medycyny Pracy i Zdrowia Środowiskowego w Sosnowcu. Dyrektor: dr n. med. P. Brewczyński
AUTOR DO KORESPONDENCJI
Paweł Gać   

Akademia Medyczna im. Piastów Śląskich we Wrocławiu Katedra i Zakład Higieny Koło Naukowe Zdrowia Środowiskowego i Epidemiologii 50-345 Wrocław, ul. Mikulicza-Radeckiego 7 tel. (71) 784-15-08
 
Med Srod. 2011;14(1):93–104
 
SŁOWA KLUCZOWE
STRESZCZENIE ARTYKUŁU
Selenu ze względu na istotne funkcje biologiczne, a także niewielką rozpiętość między dawką niezbędną do prawidłowego funkcjonowania organizmu a jego dawką toksyczną stanowi w ostatnich latach przedmiot dużego zainteresowania toksykologów i badaczy innych dziedzin. W obecnej pracy dokonano przeglądu 55 artykułów opublikowanych w latach 2005–2010 pod kątem analizy stężenia selenu we krwi w różnych populacjach. Omówiono metodykę oznaczeń selenu we krwi, zakres stężenia selenu we krwi u osób zdrowych oraz zależności pomiędzy stężeniem selenu we krwi a występowaniem różnych jednostek chorobowych m.in. nowotworów złośliwych, chorób układu krążenia, cukrzycy oraz zakażeń wirusowych. Zdaniem autorów ważne wydaje się opracowanie i standaryzacja jednej rekomendowanej metody oznaczania stężenia selenu oraz wskazanie preferowanego materiału biologicznego do jego oznaczeń. Ponadto wskazana jest dalsza kontynuacja badań na temat znaczenia selenu dla zdrowia ludzi, która rozwiałaby istniejące w tej dziedzinie wątpliwości.

Due to its significant biological functions, as well as slight diversity between the dose essential for proper functioning of the organism and its toxic dosage, during the recent years selenium concentration constituted a subject of considerable interest as far as toxicology specialists and researchers from other branches are concerned. This thesis reviews 55 articles published between 2005 and 2010 and focuses on the analysis concerning blood selenium concentration in various populations. Methodology related with various manners of marking blood selenium level, scope of blood selenium concentrations in healthy people, as well as dependence between blood selenium concentration and the occurrence of various diseases, such as malignant tumours, diseases of circulatory system, diabetes and viral infections. According to the authors, what seems important is the elaboration and standardisation of the method used to mark selenium concentration and indication of preferred biological material for marking the above. What is more, further follow up of the study focusing on significance of selenium on people health is recommended, as this would resolve all doubts within this field.
 
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