PL EN
PRACA ORYGINALNA
 
SŁOWA KLUCZOWE
DZIEDZINY
STRESZCZENIE
Introduction and objective:
Toxocariasis is a common but neglected zoonotic disease caused by the larval stage of Toxocara species. The aim of this study is to highlight the sero-epidemiology of Toxocara canis infection in the general population of Alborz Province, Iran.

Material and methods:
Anti-Toxocara canis antibodies were tested in 234 studied inhabitants by enzyme-linked immunosorbent assay (ELISA). Demographic characteristics and consent were obtained from each individual.

Results:
In total, 33 (14.1%) of the 234 participants (mean age 19.6±8.7 years) had anti-Toxocara canis antibodies. Prevalence of infection was higher in males (16.2%) than females (12.4%). High-titer antibodies were most prevalent among the subjects aged ≤ 20 years, and showed statistical significance (p=0.001). There was significant association between the presence of Toxocara antibodies and the place of residence, keeping dog at home, and contact with contaminated soils (p<0.05). This is the first report of the sero-prevalence and contributing factors for Toxocara canis infection in the general population in Alborz Province.

Conclusions:
These data confirm the importance of diagnosing human toxocariasis in this region. The findings, in addition to the hygienic status of the population, can be representative of the environmental and animal contamination. Necessary education to avoid contact with suspicious dog and non-contact with soil from infancy should be considered as preventive measures for Toxocara infection.

 
REFERENCJE (20)
1.
Magnaval JF, Glickman LT, Dorchies P, Morassin B. Highlights of human toxocariasis. Korean J Parasitol. 2001; 39(1): 1–11. http://doi.org/10.3347/kjp.200....
 
2.
Despommier D. Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects. Clin Microbiol Rev. 2003; 16 (2): 265–272. http://doi.org/10.1128/cmr.16.....
 
3.
Zibaei M, Sadjjadi SM, Jahadi-Hosseini SH. Toxocara cati larvae in the eye of a child: a case report. Asian Pac J Trop Biomed. 2014; 4 (Supl 1): S53-S55. http://doi.org/10.12980/APJTB.....
 
4.
Raissi V, Saber V, Zibaei M, Bahadory S, Akhlaghi E, Raeisi O, Aslani R, Shamsi L, Graili A, Ibrahim A. Comparison of the prevalence of Toxocara spp. eggs in public parks soils in different seasons, from 2017 to 2018, Tehran Province, Iran. Clin Epidemiol Global Health. 2020; 4 (8): 450–454. https://doi.org/10.1016/j.cegh....
 
5.
Smith H, Holland CV, Taylor M, Magnaval J, Schantz P, Maizels R. How common is human toxocariasis? Towards standardizing our knowledge. Trends Parasitol. 2009; 25(4): 182–188. http://doi.org/10.1016/j.pt.20....
 
6.
Fu CJ, Chuang TW, Lin HS, Wu CH, Liu YC, Langinlur MK, et al. Seroepidemiology of Toxocara canis infection among primary schoolchildren in the capital area of the Republic of the Marshall Islands. BMC Infect Dis. 2014; 14 (1): 261. http://doi.org/10.1186/1471-23....
 
7.
Eslahi AV, Badri M, Khorshidi A, Majidiani H, Hooshmand E, Hosseini H, et al. Prevalence of Toxocara and Toxascaris infection among human and animals in Iran with meta-analysis approach. BMC Infect Dis. 2020; 20(1): 20. http://doi.org/10.1186/s12879-....
 
8.
Zibaei M, Bahadory S, Cardillo N, Khatami AR. Soil contamination with eggs of Toxocara species in public parks of Karaj, Iran. Int J Enteric Pathogs. 2017; 5 (2): 45–48. http://doi.org/10.15171/ijep.2....
 
9.
Zibaei M Alemi, M, Cardillo NM, Derafshi H, Miahipour A, Bahadory, et al. Human toxocariasis seroprevalence among patients with uveitis in Alborz Province, Iran. Ann Agric Environ Med. 2019; 26(1): 154–158. http://doi.org/10.26444/aaem/1....
 
10.
Holland CV, O’Lorcain P, Taylor MR, Kelly A. Seroepidemiology of toxocariasis in school children. Parasitology. 1995; 110(Pt5): 535–545. http://doi.org/10.1017/s003118....
 
11.
Ghorbani-Ranjbary A, Ghorbani-Ranjbary N, Varzandian S, Ghorbani-Ranjbary Z. Frequency of anti-Toxocara antibodies in students with chronic cough and eosinophilia in a rural Area of Shiraz, Iran. Zahedan J Res Med Sci. 2015; 17(1): 15–18. https://sites.kowsarpub.com/zj....
 
12.
Fan CK, Liao CW, Kao TC, Li MH, Du WY, Su KE. Sero-epidemiology of Toxocara canis infection among aboriginal schoolchildren in the mountainous areas of northeastern Taiwan. Ann Trop Med Parasitol. 2005; 99(6), 593–600. http://doi.org/10.1179/1364859....
 
13.
Fajutag AJ, Paller VG. Toxocara egg soil contamination and its seroprevalence among public school children in Los Banos, Laguna, Philippines. Southeast Asian J Trop Med Public Health. 2013; 44(4): 551–560. https://www.tm.mahidol.ac.th/s....
 
14.
Lee JY, Yang MH, Hwang JH, Kang M, Paeng JW, Yune S, et al. The prevalence of toxocariasis and diagnostic value of serologic tests in asymptomatic Korean adults. Allergy Asthma Immunol Res. 2015; 7(5): 467–475. http://doi.org/10.4168/aair.20....
 
15.
Phasuk N, Punsawad C. Seroprevalence of Toxocara canis infection and associated risk factors among primary schoolchildren in rural Southern Thailand. Trop Med Health. 2020; 48(2): 23. http://doi.org/10.1186/s41182-....
 
16.
Sozen H, Citil BE, Caylak S, Gokmen AA, Kaya S, Demirci M, et al. Seroepidemiological study of toxocariasis among volunteers animal husbandry workers and veterinary in southern Anatolia in Turkey in 2014. Iran J Parasitol. 2015; 10(3): 473–481. https://ijpa.tums.ac.ir/index.....
 
17.
Skulinova K, Novak J, Kasny M, Kolarova L. Seroprevalence of larval toxocarosis in the Czech 6Republic. Acta Parasitol. 2020; 65(1): 68–76. http://doi.org/10.2478/s11686-....
 
18.
Arefkhah N, Shadzi MR, Mikaeili F, Sarkari B, Esfandiari F, Goudarzi F. Seroprevalence and associated risk factors of toxocariasis among nomads in Boyer-Ahmad County, southwest Iran. Trans R Soc Trop Med Hyg. 2020: 114(5): 372–377. http://doi.org/10.1093/trstmh/....
 
19.
Rezaiemanesh MR, Afzalaghaee M, Hamidi S, Eshaghzadeh A, Paydar M, Hejazi SH. Prevalence of toxocariasis and its related risk factors in humans, dogs and cats in northeastern Iran: a population-based study. Trans R Soc Trop Med Hyg. 2019: 113(7): 399–409. http://doi.org/10.1093/trstmh/....
 
20.
Berrett AN, Erickson LD, Gale SD, Stone A, Brown BL, Hedges DW. Toxocara Seroprevalence and associated risk factors in the United States. Am J Trop Med Hyg. 2017; 97(6): 1846–1850. http://doi.org/10.4269/ajtmh.1....
 
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