REVIEW PAPER
DNA repair genes polymorphisms and damages induced by lead – a literature review
 
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Instytut Medycyny Pracy i Zdrowia Środowiskowego. Dyrektor: dr n. med. P. Z. Brewczyński
CORRESPONDING AUTHOR
Elżbieta Olewińska   

Pracownia Toksykologii Genetycznej Instytut Medycyny Pracy i Zdrowia Środowiskowego ul. Kościelna 13; 41-200 Sosnowiec tel. 32 266 08 85; fax. 32 266 11 24
 
Med Srod. 2014;17(2):69–74
 
KEYWORDS
ABSTRACT
Lead is a toxic metal, which due to its superb properties is used in many industries. Due to the wide spectrum of its effects to human body it is very important to enhance the knowledge on the mechanisms of lead’s toxicity as well as to identify genetic determinants of defense against the harmful effects. DNA repair is one of the most important defense mechanisms against damage induced by lead. Gene polymorphisms may influence the recovery rate and recovery efficiency, and thus shape the individual susceptibility to lead exposure.
 
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